Articles 2018

Hydra Mesoglea Proteome Identifies Thrombospondin as a Conserved Component Active in Head Organizer Restriction. Lommel M, Strompen J, Hellewell AL, Balasubramanian GP, Christofidou ED, Thomson AR, Boyle AL, Woolfson DN, Puglisi K, Hartl M, Holstein TW, Adams JC, Özbek S. Sci Rep. 2018 Aug 6;8(1):11753. PMID:30082916


Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice. Leibing T, Géraud C, Augustin I, Boutros M, Augustin HG, Okun JG, Langhans CD, Zierow J, Wohlfeil SA, Olsavszky V, Schledzewski K, Goerdt S, Koch PS. Hepatology. 2018 Aug;68(2):707-722. PMID:29059455


Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates. Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S. Elife. 2018 Jul 31;7. PMID:30060804


Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification. Melnik S, Dvornikov D, Müller-Decker K, Depner S, Stannek P, Meister M, Warth A, Thomas M, Muley T, Risch A, Plass C, Klingmüller U, Niehrs C, Glinka A. Cell Discov. 2018 Jul 3;4:37. PMID: 29977599


The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium. Schlereth K, Weichenhan D, Bauer T, Heumann T, Giannakouri E, Lipka D, Jaeger S, Schlesner M, Aloy P, Eils R, Plass C, Augustin HG. Elife. 2018 May 11;7. PMID:29749927


Postnatal Skeletal Deletion of Dickkopf-1 Increases Bone Formation and Bone Volume in Male and Female Mice, Despite Increased Sclerostin Expression. Colditz J, Thiele S, Baschant U, Niehrs C, Bonewald LF, Hofbauer LC, Rauner M. J Bone Miner Res. 2018 May 7. PMID:29734465


Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation. Sonnen KF, Lauschke VM, Uraji J, Falk HJ, Petersen Y, Funk MC, Beaupeux M, François P, Merten CA, Aulehla A. Cell. 2018 Feb 22;172(5):1079-1090.e12. PMID:29474908


β-catenin-independent regulation of Wnt target genes by RoR2 and ATF2/ATF4 in colon cancer cells. Voloshanenko O, Schwartz U, Kranz D, Rauscher B, Linnebacher M, Augustin I, Boutros M. Sci Rep. 2018 Feb 16;8(1):3178. PMID:29453334


DKK3 (Dickkopf 3) Alters Atherosclerotic Plaque Phenotype Involving Vascular Progenitor and Fibroblast Differentiation Into Smooth Muscle Cells. Karamariti E, Zhai C, Yu B, Qiao L, Wang Z, Potter CMF, Wong MM, Simpson RML, Zhang Z, Wang X, Del Barco Barrantes I, Niehrs C, Kong D, Zhao Q, Zhang Y, Hu Y, Zhang C, Xu Q. Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):425-437. PMID:29284609


ERAD-dependent control of the Wnt secretory factor Evi. Glaeser K, Urban M, Fenech E, Voloshanenko O, Kranz D, Lari F, Christianson JC, Boutros M. EMBO J. 2018 Feb 15;37(4). PMID:29378775


Widespread Rewiring of Genetic Networks upon Cancer Signaling Pathway Activation. Billmann M, Chaudhary V, ElMaghraby MF, Fischer B, Boutros M. Cell Syst. 2018 Jan 24;6(1):52-64.e4. PMID:29199019


Revealing age-related changes of adult hippocampal neurogenesis using mathematical models. Ziebell F, Dehler S, Martin-Villalba A, Marciniak-Czochra A. Development. 2018 Jan 8;145(1). PMID:29229768


Reviews 2018

Making head or tail of cnidarian hox gene function. Rentzsch F, Holstein TW. Nat Commun. 2018 Jun 5;9(1):2187. PMID:29872045


A Cell-Based Assay for Mitotic Spindle Orientation. Glaubke E, Bastians H. Methods Mol Biol. 2018;1787:67-75. PMID:29736710


The Mingle-Mangle of Wnt Signaling and Extracellular Vesicles: Functional Implications for Heart Research. Gross JC, Zelarayán LC. Front Cardiovasc Med. 2018 Feb 22;5:10. PMID:29564334


Articles 2017

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families. Voloshanenko O, Gmach P, Winter J, Kranz D, Boutros M. FASEB J. 2017 Nov;31(11):4832-4844. PMID:28733458


Neutral sphingomyelinases control extracellular vesicles budding from the plasma membrane. Menck K, Sönmezer C, Worst TS, Schulz M, Dihazi GH, Streit F, Erdmann G, Kling S, Boutros M, Binder C, Gross JC. J Extracell Vesicles. 2017 Sep 26;6(1):1378056. PMID:29184623


Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C. Dev Cell. 2017 Oct 9;43(1):71-82.e6. doi: 10.1016/j.devcel.2017.09.011. PMID:29017031


Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6. Berger BS, Acebron SP, Herbst J, Koch S, Niehrs C. EMBO Rep. 2017 May;18(5):712-725. PMID:28341812