Publications

Articles 2018

The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ. Chang L, Azzolin L, Di Biagio D, Zanconato F, Battilana G, Lucon Xiccato R, Aragona M, Giulitti S, Panciera T, Gandin A, Sigismondo G, Krijgsveld J, Fassan M, Brusatin G, Cordenonsi M, Piccolo S. Nature. 2018 Nov;563(7730):265-269. doi: 10.1038/s41586-018-0658-1. Epub 2018 Oct 31. PMID:30401838

 

Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4. Zanconato F, Battilana G, Forcato M, Filippi L, Azzolin L, Manfrin A, Quaranta E, Di Biagio D, Sigismondo G, Guzzardo V, Lejeune P, Haendler B, Krijgsveld J, Fassan M, Bicciato S, Cordenonsi M, Piccolo S. Nat Med. 2018 Oct;24(10):1599-1610. doi: 10.1038/s41591-018-0158-8. Epub 2018 Sep 17. PMID:30224758

 

Hydra Mesoglea Proteome Identifies Thrombospondin as a Conserved Component Active in Head Organizer Restriction. Lommel M, Strompen J, Hellewell AL, Balasubramanian GP, Christofidou ED, Thomson AR, Boyle AL, Woolfson DN, Puglisi K, Hartl M, Holstein TW, Adams JC, Özbek S. Sci Rep. 2018 Aug 6;8(1):11753. PMID:30082916

 

Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice. Leibing T, Géraud C, Augustin I, Boutros M, Augustin HG, Okun JG, Langhans CD, Zierow J, Wohlfeil SA, Olsavszky V, Schledzewski K, Goerdt S, Koch PS. Hepatology. 2018 Aug;68(2):707-722. PMID:29059455

 

Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates. Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S. Elife. 2018 Jul 31;7. PMID:30060804

 

Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification. Melnik S, Dvornikov D, Müller-Decker K, Depner S, Stannek P, Meister M, Warth A, Thomas M, Muley T, Risch A, Plass C, Klingmüller U, Niehrs C, Glinka A. Cell Discov. 2018 Jul 3;4:37. PMID: 29977599

 

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium. Schlereth K, Weichenhan D, Bauer T, Heumann T, Giannakouri E, Lipka D, Jaeger S, Schlesner M, Aloy P, Eils R, Plass C, Augustin HG. Elife. 2018 May 11;7. PMID:29749927

 

Postnatal Skeletal Deletion of Dickkopf-1 Increases Bone Formation and Bone Volume in Male and Female Mice, Despite Increased Sclerostin Expression. Colditz J, Thiele S, Baschant U, Niehrs C, Bonewald LF, Hofbauer LC, Rauner M. J Bone Miner Res. 2018 May 7. PMID:29734465

 

Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation. Sonnen KF, Lauschke VM, Uraji J, Falk HJ, Petersen Y, Funk MC, Beaupeux M, François P, Merten CA, Aulehla A. Cell. 2018 Feb 22;172(5):1079-1090.e12. PMID:29474908

 

β-catenin-independent regulation of Wnt target genes by RoR2 and ATF2/ATF4 in colon cancer cells. Voloshanenko O, Schwartz U, Kranz D, Rauscher B, Linnebacher M, Augustin I, Boutros M. Sci Rep. 2018 Feb 16;8(1):3178. PMID:29453334

 

DKK3 (Dickkopf 3) Alters Atherosclerotic Plaque Phenotype Involving Vascular Progenitor and Fibroblast Differentiation Into Smooth Muscle Cells. Karamariti E, Zhai C, Yu B, Qiao L, Wang Z, Potter CMF, Wong MM, Simpson RML, Zhang Z, Wang X, Del Barco Barrantes I, Niehrs C, Kong D, Zhao Q, Zhang Y, Hu Y, Zhang C, Xu Q. Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):425-437. PMID:29284609

 

ERAD-dependent control of the Wnt secretory factor Evi. Glaeser K, Urban M, Fenech E, Voloshanenko O, Kranz D, Lari F, Christianson JC, Boutros M. EMBO J. 2018 Feb 15;37(4). PMID:29378775

 

Widespread Rewiring of Genetic Networks upon Cancer Signaling Pathway Activation. Billmann M, Chaudhary V, ElMaghraby MF, Fischer B, Boutros M. Cell Syst. 2018 Jan 24;6(1):52-64.e4. PMID:29199019

 

Revealing age-related changes of adult hippocampal neurogenesis using mathematical models. Ziebell F, Dehler S, Martin-Villalba A, Marciniak-Czochra A. Development. 2018 Jan 8;145(1). PMID:29229768

 

Reviews 2018

Making head or tail of cnidarian hox gene function. Rentzsch F, Holstein TW. Nat Commun. 2018 Jun 5;9(1):2187. PMID:29872045

 

A Cell-Based Assay for Mitotic Spindle Orientation. Glaubke E, Bastians H. Methods Mol Biol. 2018;1787:67-75. PMID:29736710

 

The Mingle-Mangle of Wnt Signaling and Extracellular Vesicles: Functional Implications for Heart Research. Gross JC, Zelarayán LC. Front Cardiovasc Med. 2018 Feb 22;5:10. PMID:29564334

 

Articles 2017

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families. Voloshanenko O, Gmach P, Winter J, Kranz D, Boutros M. FASEB J. 2017 Nov;31(11):4832-4844. PMID:28733458

 

Neutral sphingomyelinases control extracellular vesicles budding from the plasma membrane. Menck K, Sönmezer C, Worst TS, Schulz M, Dihazi GH, Streit F, Erdmann G, Kling S, Boutros M, Binder C, Gross JC. J Extracell Vesicles. 2017 Sep 26;6(1):1378056. PMID:29184623

 

Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. Kirsch N, Chang LS, Koch S, Glinka A, Dolde C, Colozza G, Benitez MDJ, De Robertis EM, Niehrs C. Dev Cell. 2017 Oct 9;43(1):71-82.e6. doi: 10.1016/j.devcel.2017.09.011. PMID:29017031

 

Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6. Berger BS, Acebron SP, Herbst J, Koch S, Niehrs C. EMBO Rep. 2017 May;18(5):712-725. PMID:28341812