Apl. Prof. Dr. Suat Özbek

Heidelberg University
Centre for Organismal Studies (COS)
Department Molecular Evolution and Genomics
Im Neuenheimer Feld 230
D-69120 Heidelberg

 

E-mail: suat.oezbek@cos.uni-heidelberg.de

 

Homepage

Scientific CV

Academic education and professional career

2017
2011
2005

2004
2000

2000

Appointment as Adjunct Professor at Heidelberg University, Germany
Permanent position as Senior Lecturer and group leader (COS), Dept. Molecular Evolution and Genomics, Heidelberg University, Germany
Group leader, Zoological Institute Heidelberg University, Germany

Habilitation in Biochemistry/Biophysics, University of Basel, Switzerland
Postdoc, Biozentrum Basel, Switzerland, with Prof. Dr. Jürgen Engel

PhD, University of Mainz, Germany, Advisor: Prof. Dr. Stefan Rose-John,

Publications

  1. Ziegler B., Trageser T., Kumar S., Kling S., Yiallouros I., Mercker M., Marciniak-Czochra A., Warnken U., Schnölzer M., Stöcker W., Hartl M., Stetefeld J., Holstein T. and S. Ozbek. A Wnt-specific astacin proteinase controls head formation in Hydra. bioRxiv 2020. doi.org/10.1101/2020.08.13.247569
  2. Shoemark, D.K., B. Ziegler, H. Watanabe, J. Strompen, R.P. Tucker, S. Ozbek*, and J.C. Adams*. 2019. Emergence of a Thrombospondin Superfamily at the Origin of Metazoans. Mol Biol Evol. 36:1220- 1238. PMID: 30863851. (*shared senior authorship)
  3. Mattes, B., Y. Dang, G. Greicius, L.T. Kaufmann, B. Prunsche, J. Rosenbauer, J. Stegmaier, R. Mikut, S. Ozbek, G.U. Nienhaus, A. Schug, D.M. Virshup, and S. Scholpp. 2018. Wnt/PCP controls spreading of Wnt/beta-catenin signals by cytonemes in vertebrates. Elife. 7. PMID: 30863851.
  4. Lommel, M., J. Strompen, A.L. Hellewell, G.P. Balasubramanian, E.D. Christofidou, A.R. Thomson, A.L. Boyle, D.N. Woolfson, K. Puglisi, M. Hartl, T.W. Holstein, J.C. Adams, and S. Ozbek. 2018. Hydra Mesoglea Proteome Identifies Thrombospondin as a Conserved Component Active in Head Organizer Restriction. Sci Rep. 8:11753. PMID: 30082916
  5. Brinkmann, E.M., B. Mattes, R. Kumar, A.I. Hagemann, D. Gradl, S. Scholpp, H. Steinbeisser, L.T. Kaufmann, and S. Ozbek. 2016. Secreted Frizzled-related Protein 2 (sFRP2) Redirects Non-canonical Wnt Signaling from Fz7 to Ror2 during Vertebrate Gastrulation. J Biol Chem. 291:13730-13742. PMID: 30082916
  6. Beckmann, A., S. Xiao, J.P. Muller, D. Mercadante, T. Nuchter, N. Kroger, F. Langhojer, W. Petrich, T.W. Holstein, M. Benoit, F. Grater, and S. Ozbek. 2015. A fast recoiling silk-like elastomer facilitates nanosecond nematocyst discharge. BMC Biol. 13:3. PMID: 25592740
  7. Watanabe, H., H.A. Schmidt, A. Kuhn, S.K. Hoger, Y. Kocagoz, N. Laumann-Lipp, S. Ozbek, and T.W. Holstein. 2014. Nodal signalling determines biradial asymmetry in Hydra. Nature. PMID: 25156256
  8. Kumar, S., M. Zigman, T.R. Patel, B. Trageser, J.C. Gross, K. Rahm, M. Boutros, D. Gradl, H. Steinbeisser, T. Holstein, J. Stetefeld, and S. Ozbek. 2014. Molecular dissection of Wnt3a-Frizzled8 interaction reveals essential and modulatory determinants of Wnt signaling activity. BMC Biol. 12:44. PMID: 24885675
  9. Meier, S., P.R. Jensen, C.N. David, J. Chapman, T.W. Holstein, S. Grzesiek, and S. Ozbek. 2007. Continuous molecular evolution of protein-domain structures by single amino acid changes. Curr Biol. 17:173- 178. PMID: 17240343
  10. Ozbek, S., J. Engel, and J. Stetefeld. 2002. Storage function of cartilage oligomeric matrix protein: the crystal structure of the coiled-coil domain in complex with vitamin D(3). Embo J. 21:5960-5968. PMID: 12426368