Prof. Dr. Christof Niehrs


German Cancer Research Center (DKFZ)
Division of Molecular Embryology
Im Neuenheimer Feld 280
69120 Heidelberg



Professional career










Diploma in Biochemistry, Freie Universität Berlin
Dr. rer. nat.; EMBL, Heidelberg
Postdoctoral research with E.M. De Robertis, University of California, Los Angeles
Head of the Division of Molecular Embryology at the German Cancer Research Center, Heidelberg
Chair of Molecular Embryology (C4), German Cancer Research Center and Heidelberg University
Founding director of the Institute of Molecular Biology Mainz (IMB)

Research Interest

The Wnt growth factor signaling pathway plays an eminent role in development and stem cells. Understanding the molecular events that regulate Wnt signalling is of fundamental importance for cancer research. Yet, many aspects of the Wnt signal transduction remain elusive. Our group is using frogs and mice as model organisms to study mechanisms of Wnt signaling underlying embryonic cell differentiation. We are identifying Wnt-related developmental control genes, and are investigating their functions and regulation. Our particular interest is investigating the regulation of Wnt receptors during signaling.