Prof. Dr. Gerd Ulrich Nienhaus


Karlsruhe Institute of Technology (KIT)
Institute of Applied Physics
Wolfgang-Gaede-Str. 1
76131 Karlsruhe






Scientific CV

Academic education and professional career

since 2009
since 1997
1996 – 2009
1996 – 1997
1992 – 1996
1988 – 1989


Full Professor (W3) and Director, Institute of Applied Physics, KIT, Karlsruhe, Germany
Adjunct Professor, Physics/Biophysics, University of Illinois at Urbana-Champaign, USA
Full Professor (C4) and Director, Institute of Biophysics, University of Ulm, Germany
Visiting Professor (with Prof. Steve Chu), Stanford University, USA
Associate Professor, Physics/Biophysics, University of Illinois at Urbana-Champaign, USA
Assistant Professor, Physics/Biophysics, University of Illinois at Urbana-Champaign, USA
Vis. Res. Asst. Professor, Physics, University of Illinois at Urbana-Champaign, USA
Postdoc, University of Illinois at Urbana-Champaign, USA
Postdoc, Universities of Münster and Mainz, Germany

Dr. rer. nat., Physical Chemistry, University of Münster, Germany, Advisor: Prof. Dr. Fritz Parak

Diploma in Physics, University of Münster, Germany

Other achievements & Awards

since 2012

Member, Committee for the Allocation of Alexander von Humboldt Foundation Research Awards, Alexander von Humboldt Foundation
Member, Board of Directors, Heidelberg Karlsruhe Research Partnership (HEiKA)
Vice Dean, Faculty of Physics, Karlsruhe Institute of Technology (KIT)
Excellence in Teaching Award of the Faculty of Physics (Fakultätslehrpreis), (KIT)
Vice President of the German Biophysical Society (DGfB)
President of the DGfB
Council Member of the International Union of Pure and Applied Biophysics (IUPAB)
Member, Grant Review Board “Foundations of Biology and Medicine, Section 1:Biochemistry, Biophysics, Structural Biology and Bioinformatics” (DFG)
Spokesman, Conference of Physics Departments in Germany (KFP)
Executive Board Member (for Higher Education and Junior Scientists), German Physical Society (DPG)
Cooperation Prize Science-Industry, University of Ulm
Chairman of Commission C6 (Biological Physics) of the International Union of Pure and Applied Physics (IUPAP)
Vice Dean of the Faculty of Natural Sciences, University of Ulm
Fellow, American Association for the Advancement of Science (AAAS)
Secretary of Commission C6 (Biological Physics) of the IUPAP
Fellow, Institute of Physics (IoP, London)
Fellow, American Physical Society (APS)
Fellow, Center for Advanced Study, U Illinois
Feodor Lynen Fellow of the Alexander von Humboldt Foundation
1988 Ph. D. Prize, University of Münster


  1. Sunbul, M., J. Lackner, A. Martin, D. Englert, B. Hacene, K. Nienhaus, G.U. Nienhaus and A. Jäschke. 2020. Super-resolution RNA imaging using a rhodamine-binding aptamer with fast exchange kinetics. Nat Biotechnol. 2021 Feb 11. doi: 10.1038/s41587-020-00794-3. Online ahead of print. PMID: 33574610
  2. Gao, P., B. Prunsche, L. Zhou, K. Nienhaus, and G.U. Nienhaus. 2017. Background Suppression in Fluorescence Nanoscopy with Stimulated Emission Double Depletion. Nat. Photon. 11:163-169.
  3. Manz, C., A.Y. Kobitski, A. Samanta, B. G. Keller, A. Jäschke, and G.U. Nienhaus. 2017. Single-Molecule FRET Reveals the Energy Landscape of the Full-Length SAM-I Riboswitch. Nat. Chem. Biol. 13:1172-1178. PMID:28920931.
  4. Hedde, P.N., R.M. Dörlich, R. Blomley, D. Gradl, E. Oppong, A.C.B. Cato, and G.U. Nienhaus. 2013. Stimulated emission depletion-based raster image correlation spectroscopy reveals biomolecular dynamics in live cells. Nat. Commun. 4:2093. PMID:23803641.
  5. Fuchs, J., S. Boehme, F. Oswald, P.N. Hedde, M. Krause, J. Wiedenmann, and G.U. Nienhaus. 2010. A photoactivatable marker protein for pulse-chase imaging with superresolution. Nat. Methods. 7:627-630. PMID:20601949.
  6. Hedde, P.N., J. Fuchs, F. Oswald, J. Wiedenmann, and G.U. Nienhaus. 2009. Online image analysis software for photoactivation localization microscopy. Nat. Methods. 6:689-690. PMID:19789527.
  7. Röcker, C., M. Pötzl, F. Zhang, W.J. Parak, and G.U. Nienhaus. 2009. Protein Monolayer Formation on Colloidal Nanoparticles: A Quantitative Fluorescence Study. Nat. Nanotechnol. 4:577-580. PMID:19734930.
  8. Wiedenmann, J., S. Ivanchenko, F. Oswald, F. Schmitt, C. Röcker, A. Salih, K.D. Spindler, and G.U. Nienhaus. 2004. EosFP, a Fluorescent Marker Protein with UV-Inducible Green-to-Red Fluorescence Conversion. Proc. Natl. Acad. Sci. USA. 101:15905-15910. PMID:15505211.
  9. Ostermann, A., R. Waschipky, F.G. Parak, and G.U. Nienhaus. 2000. Ligand Binding and Conformational Motions in Myoglobin. Nature. 404:205-208. PMID:10724176.
  10. Nienhaus, G.U., J. Heinzl, E. Huenges, and F. Parak. 1989. Protein Crystal Dynamics Studied by Time resolved Analysis of X-ray Diffuse Scattering. Nature. 338:665-666