Medical Faculty Mannheim
Dept. of Vascular Biology and Tumor Angiogenesis and
German Cancer Research Center (DKFZ)
Div. of Vascular Oncology and Metastasis
Hellmut G. Augustin is Professor of Vascular Biology at the Medical Faculty Mannheim of Heidelberg University and Head of the Division for Vascular Oncology and Metastasis Research at the German Cancer Research Center (DKFZ) in Heidelberg, Germany, since 2006. Trained as a Veterinary Pathologist at the School of Veterinary Medicine Hannover, Germany (1987) and as PhD in Experimental Pathology at Cornell University, Ithaca, NY, USA (1992), he worked previously as Assistant Professor at the University of Göttingen, Germany (1993-2000) and as Department Head at the Tumor Biology Center in Freiburg, Germany (2001-2006). His laboratory (www.angiolab.de) studies 1.) the molecular mechanisms of physiological blood vessel formation, assembly, and maturation focusing on angiogenesis regulating receptor tyrosine kinases, most notably on the Angiopoietin-Tie ligand-receptor system as well as on other selected novel candidate molecules, 2.) the mechanisms of organotypic vascular differentiation and angiocrine signaling studying the lung and liver vasculature as prototypic vascular beds, 3.) the molecular mechanisms of tumor progression focusing on tumor-vessel interactions during metastasis, and 4.) translational tumor angiogenesis experiments aimed at defining the therapeutic window of stromal targeted therapies.