Prof. Dr. Jeroen Krijgsveld

Heidelberg University/ Medical Faculty Heidelberg
Division Proteomics of Stem Cells and Cancer / DKFZ
Im Neuenheimer Feld 581
69120 Heidelberg




Scientific CV

Academic education and professional career

since 2016


since 2016








Full Professor for Proteomics, Heidelberg University, Medical Faculty Heidelberg, Excellence Cluster CellNetworks, Heidelberg, Germany
Head of Division, Proteomics of Stem Cells and Cancer, German Cancer Research Center, Heidelberg, Germany
Research Team Leader and Head of the Proteomics Core Facilty, European MolecularBiology Laboratory (EMBL), Heidelberg, Germany
Assistant Professor, Utrecht University, Utrecht, The Netherlands
Postdoctoral research with Prof. Steven Gygi, Harvard Medical School, Boston, USA
Postdoctoral research with Prof. Albert Heck, Utrecht University, Utrecht, The Netherlands
Postdoctoral research with Prof.Frans Nijkamp, Utrecht University, Utrecht, The Netherlands

Dr., University of Amsterdam, The Netherlands. Advisor: Prof. J. Dankert.

Other achievements & Awards

since 2020
since 2012
since 2007

Coordinator of research consortium SMART-CARE, one of the four BMBF-funded ‘Forschungskerne für Massenspektrometrie in der Systemmedizin’
‘Mass spectrometry in the life sciences’ award of the German Mass Spectrometry Society (Deutsche Gesellschaft für Massenspektrometrie, DGMS), for ‘outstanding method developments in, and applications of, mass spectrometry in the life sciences’
Inaugural award from the Netherlands Society for Mass Spectrometry (NVMS) for outstanding research
Member of Scientific Advisory Board FP7 program ‘SystemAge’
Associate Editor of BMC Genomics
Co-founder and board member of the ‘Proteome biology of Stem Cells’ initiative, resorting under the Human Proteome Organization (HUPO)
Board member of the Association of Biomolecular Research Facilities (ABRF) ProteomicsResearch Group
VIDI grant from NWO (Netherlands Organisation for Scientific Research)
Board member of the Netherlands Society for Mass Spectrometry (NVMS)
Horizon Breakthrough grant from NWO (Netherlands Organisation for Scientific Research)
High Potential grant from Utrecht University (in collaboration with Prof. Frank Holstege)
NWO Genomics Fellowship (Netherlands Genomics Initiative)
Project leader in the program ‘Quantitative proteomics’ of the Netherlands Proteomics Center
Manager of the Analytical Expertise Center of the Netherlands Proteomics Center
Co-founder and board member of the Netherlands Proteomics Platform (part of Dutch Biochemical Society)


  1. Rafiee, M.-R., G. Sigismondo, M. Kalxdorf, L. Förster, B. Brügger, J. Béthune, and J. Krijgsveld. 2020. Protease-resistant streptavidin for interaction proteomics. Mol. Syst. Biol. 16:e9370. PMID: 32400114
  2. Müller, T., M. Kalxdorf, R. Longuespée, D.N. Kazdal, A. Stenzinger, and J. Krijgsveld. 2020. Automated sample preparation with SP3 for low-input clinical proteomics. Mol. Syst. Biol. 16:e9111. PMID: 32129943
  3. Bunina, D., N. Abazova, N. Diaz, K.-M. Noh, J. Krijgsveld#, and J.B. Zaugg#. 2020. Genomic Rewiring of SOX2 Chromatin Interaction Network during Differentiation of ESCs to Postmitotic Neurons. Cell Syst. 10:480-494.e8. PMID 32553182
  4. Selkrig, J., N. Li, A. Hausmann, M.S.J. Mangan, M. Zietek, A. Mateus, J. Bobonis, A. Sueki, H. Imamura, B. El Debs, G. Sigismondo, B.I. Florea, H.S. Overkleeft, N. Kopitar-Jerala, B. Turk, P. Beltrao, M.M. Savitski, E. Latz, W.-D. Hardt, J. Krijgsveld#, and A. Typas#. 2020. Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection. Nat. Microbiol.
    PMID: 32514074.
  5. Trendel, J., T. Schwarzl, R. Horos, A. Prakash, A. Bateman, M.W. Hentze, and J. Krijgsveld. 2019. The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest. Cell. 176:391-403.e19.
    PMID: 30528433
  6. Cagnetta, R., C.K. Frese, T. Shigeoka, J. Krijgsveld#, and C.E. Holt#. 2018. Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome. Neuron. 99:29-46.e4. PMID: 30008298
  7. Rafiee, M.-R., C. Girardot, G. Sigismondo, and J. Krijgsveld. 2016. Expanding the Circuitry of Pluripotency by Selective Isolation of Chromatin-Associated Proteins. Mol. Cell. 64:624–635. PMID 27773674
  8. Hughes, C.S., S. Foehr, D. Garfield, E.E. Furlong, L.M. Steinmetz, and J. Krijgsveld. 2014. Ultrasensitive proteome analysis using paramagnetic bead technology. Mol. Syst. Biol. 10:757. PMID: 25358341
  9. Castello, A., B. Fischer, K. Eichelbaum, R. Horos, B.M. Beckmann, C. Strein, N.E. Davey, D.T. Humphreys, T. Preiss, L.M. Steinmetz, J. Krijgsveld#, and M.W. Hentze#. 2012. Insights into RNA biology froman atlas of mammalian mRNA-binding proteins. Cell. 149:1393–406. PMID 22658674
  10. Eichelbaum, K., M. Winter, M. Berriel Diaz, S. Herzig, and J. Krijgsveld. 2012. Selective enrichment of newly synthesized proteins for quantitative secretome analysis. Nat. Biotechnol. 30:984–90. PMID: 23000932

(# Joint senior authors)