Prof. Dr. Thomas Holstein

Heidelberg University
Centre for Organismal Studies (COS)
Department of Molecular Evolution and Genomics
Im Neuenheimer Feld 230
D-69120 Heidelberg

 

E-mail: thomas.holstein@cos.uni-heidelberg.de

 

Homepage

Scientific CV

Academic education and professional career

since 2004

1998-2004
1993-1998
1987-1992
1983-1987
1980-1983

1991

1980

Professor of Molecular Evolution and Genomics (C4), Zoological Institute and Centre for Organismal Studies (COS), Heidelberg University, Germany
Professor of Cell Biology (C4), Zoological Institute, Darmstadt University (TU), Germany
Professor of Cell and Developmental Biology (C3), Zoological Institute, Frankfurt University, Germany
Research Associate (C2), Zoological Institute, Munich University (LMU), Germany
Research Fellow, Zoological Institute, Munich University (LMU), Germany
Research Fellow, Zoological Institute, Zurich University, Switzerland

Dr.rer.nat.habil., Munich University (LMU), Germany
Dr.phil., Vienna University, Austria

Other achievements & Awards

since 2020
since 2018
2015-2020
2013-2019
2013-2014
2013-2015
2012-2018
2011-2012
2010-2014
2009-2014
since 2007
2007-2012
since 2006
2006-2013
since 2005

2004-2012
2004-2011
2002-2004
1998-2000
1996-1997
1993-1995

Member of the Academic Advisory Council, Heidelberg University
Visiting professor for Developmental Biology, Kyoto University, Japan
President of the Heidelberg Academy of Sciences and Humanities
Member of the Senate Committee on Research Training Groups, DFG
Fellow of the Marsilius Kolleg, Heidelberg University
Head of the Math.-Nat. Class of the Heidelberg Academy of Sciences and Humanities
Directorate Member of the “Heidelberg-Karlsruhe Research Partnership” (HEiKA)
Fellow of the Marsilius Kolleg, Heidelberg University
Vice-Coordinator of the SFB 873
Vice-Coordinator of the DFG FOR1036
Elected Member of the of the Heidelberg Academy of Sciences and Humanities
Dean of the Faculty of Biosciences, Heidelberg University
Member and Vice-Coordinator of the Heidelberg Excellence Cluster Cellular Networks
Member of the Heidelberg Molecular Life Science (HMLS) Steering committee
Founder and Head of Nikon Imaging Center at Heidelberg University

Member and Deputy Spokesperson of the DFG Reviewing Board 203-06
Director of the Zoological Institute, Heidelberg University
Director of the Zoological Institute, Darmstadt University (TU)
Dean of the Faculty of Biology, Darmstadt University (TU)
Offers for full professorships at the Universities of Karlsruhe and Vienna, declined
Visiting professor for Developmental Biology, University of Vienna, Austria

Publications

  1. Tursch, A., M. Lommel, N. Bartsch, and T.W. Holstein. 2020. MAPK signaling links the injury response to Wnt-regulated patterning in Hydra regeneration. BioRxiv, https://doi.org/10.1101/2020.07.06.189795
  2. Holstein TW. 2019. What makes flatworms go to pieces. Nature. 572: 593‐594. PMID: 31444489
  3. Petersen, H.O.*, S.K. Hoger*, M. Looso, T. Lengfeld, A. Kuhn, U. Warnken, C. Nishimiya-Fujisawa, M. Schnolzer, M. Kruger, S. Ozbek, O. Simakov, and T.W. Holstein. 2015. A Comprehensive Transcriptomic and Proteomic Analysis of Hydra Head Regeneration. Mol Biol Evol. Apr 3. pii:msv079. PMID: 25841488. (*co-first authors)
  4. Watanabe, H., H.A. Schmidt, A. Kuhn, S.K. Hoger, Y. Kocagoz, N. Laumann-Lipp, S. Ozbek, and T.W. Holstein. 2014. Nodal signalling determines biradial asymmetry in Hydra. Nature. 515:112-115. PMID: 25156256.
  5. Watanabe, H., A. Kuhn, M. Fushiki, K. Agata, S. Ozbek, T. Fujisawa, and T.W. Holstein. 2014. Sequential actions of beta-catenin and Bmp pattern the oral nerve net in Nematostella vectensis. Nat Commun. 5:5536. PMID: 25534229.
  6. Holstein, T.W. 2012. The Evolution of the Wnt Pathway. Cold Spring Harb Perspect Biol. 4:a007922. PMID: 22751150.
  7. Nakamura, Y., C.D. Tsiairis, S. Ozbek, and T.W. Holstein. 2011. Autoregulatory and repressive inputs localize Hydra Wnt3 to the head organizer. Proc Natl Acad Sci U S A. 108:9137-9142. PMID: 21576458.
  8. Lengfeld, T., H. Watanabe, O. Simakov, D. Lindgens, L. Gee, L. Law, H.A. Schmidt, S. Ozbek, H. Bode, and T.W. Holstein. 2009. Multiple Wnts are involved in Hydra organizer formation and regeneration. Dev Biol. 330:186-199. PMID: 19217898.
  9. Kusserow, A., K. Pang, C. Sturm, M. Hrouda, J. Lentfer, H.A. Schmidt, U. Technau, A. von Haeseler, B. Hobmayer, M.Q. Martindale, and T.W. Holstein. 2005. Unexpected complexity of the Wnt gene family in a sea anemone. Nature. 433:156-160. PMID: 15650739. (Cover)
  10. Hobmayer, B., F. Rentzsch, K. Kuhn, C.M. Happel, C. Cramer von Laue, P. Snyder, U. Rothbacher, and T.W. Holstein. 2000. WNT signalling molecules act in axis formation in the diploblastic metazoan Hydra. Nature. 407:186-189. PMID: 11001056.

(*shared authorship)