Projects of the SFB1324

Project A1: Mechanisms of Wnt protein secretion in polarized epithelia
Michael Boutros, Heidelberg University


Project A2: Autocrine and angiocrine vascular Wnt signaling in tumor progression and metastasis
Hellmut Augustin, Heidelberg University


Project A3: Ykt6-dependent trafficking of Wnts
Julia Gross, University of Göttingen


Project A4: Roles of lipids in transport of Wnt proteins
Britta Brügger, Heidelberg University
Michael Boutros, Heidelberg University


Project A5: The Wnt code: Deciphering early Wnt ligand-receptor interactions
Thomas Holstein, Heidelberg University


Project A6: Quantitative fluorescence microscopy for the analysis of Wnt pathway interactions and dynamics
Gary Davidson, KIT, Karlsruhe
G. Ulrich Nienhaus, KIT, Karlsruhe


Project B1: Role of DEAD box helicases in kinase regulation during Wnt signaling
Christof Niehrs, DKFZ, Heidelberg


Project B2: Mechanism of oscillatory Wnt signaling activity during mesoderm patterning in the mouse embryo
Alexander Aulehla, EMBL, Heidelberg


Project B3: The roles of Wnt signaling during mitosis
Sergio P. Acebrón, Heidelberg University
Holger Bastians, University of Göttingen


Project B4: Wnt signaling in fate determination of retinal precursors
Jochen Wittbrodt, Heidelberg University


Project B5: Mathematical modeling of pattern formation in Wnt signaling
Anna Marciniak-Czochra, Heidelberg University


Project B6: Orchestration by the Wnt/Hippo/CD95 signalosome of stem like and EMT phenotypes
Ana Martin-Villalba, DKFZ, Heidelberg


Project B7: Uncovering novel molecular mechanisms within Wnt signaling
Irmgard Sinning, Heidelberg University


Project Z2: Advanced fluorescence microscopy
G. Ulrich Nienhaus, KIT, Karlsruhe
Ulrike Engel, Heidelberg University


Project Z3: Advanced genetic screens and genome engineering
Michael Boutros, Heidelberg University


Project Z4: Proteomics
Jeroen Krijgsveld, Heidelberg University