Review

Cracking chromatin with proteomics: From chromatome to histone modifications

cell biology post-translational modification analysis sample preparation signal transduction technology

Sigismondo G, Papageorgiou DN, Krijgsveld J. Proteomics. 2022 May 28:e2100206. doi: 10.1002/pmic.202100206. Online ahead of print. PMID: 35633285

Learn more
Research Article

Allele-specific endogenous tagging and quantitative analysis of β-catenin in colorectal cancer cells

cancer cell biology CRISPR ctnnb1 endogenous tagging FCS fluorescence correlation spectroscopy genetics genomics human β-catenin oncogenic signaling Wnt signaling
Ambrosi G, Voloshanenko O, Eckert AF, Kranz D, Nienhaus GU, Boutros M. Elife. 2022 Jan 11;11:e64498. doi: 10.7554/eLife.64498.
PMID: 35014953
Learn more
Research Article

A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling

cell biology endocytosis HGF-MET human PTPR tyrosine kinases Wnt signaling ZNRF3
Kim M, Reinhard C, Niehrs C. Elife. 2021 Sep 30;10:e70885. doi: 10.7554/eLife.70885.
PMID: 34590584
Learn more
Research Article

The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer

cell biology developmental biology human LRP6 PTPRK spemann organizer tyrosine phosphatase Wnt signaling xenopus ZNRF3

Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C. Elife. 2020 Jan 14;9. pii: e51248.

PMID: 31934854

Learn more
Research Article

Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates

cell biology cytonemes developmental biology patterning signaling filopodia trafficking Wnt signaling zebrafish

Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S. Elife. 2018 Jul 31;7.

PMID:30060804

Learn more