From injury to patterning-MAPKs and Wnt signaling in Hydra

Axis formation injury response MAPK signaling Pattern formation regeneration Wnt/β-catenin
Tursch A, Holstein TW. Curr Top Dev Biol. 2023;153:381-417. doi: 10.1016/bs.ctdb.2023.01.003. Epub 2023 Feb 9. PMID: 36967201 Review.
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Research Article

Injury-induced MAPK activation triggers body axis formation in Hydra by default Wnt signaling

Axis formation injury response MAPK signaling regeneration Wnt/beta-catenin
Tursch A, Bartsch N, Mercker M, Schlüter J, Lommel M, Marciniak-Czochra A, Özbek S, Holstein TW. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2204122119. doi: 10.1073/pnas.2204122119. Epub 2022 Aug 22. PMID: 35994642
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What makes flatworms go to pieces

flatworm regeneration Wnt signaling

Holstein TW. Nature. 2019 Aug;572(7771):593-594.

PMID: 31444489

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