Publication Tag: Wnt signaling

Research Article

Wnt signaling recruits KIF2A to the spindle to ensure chromosome congression and alignment during mitosis

chromosome alignment Dishevelled Kinesin-13 Mitosis Wnt signaling

Bufe A, García Del Arco A, Hennecke M, de Jaime-Soguero A, Ostermaier M, Lin YC, Ciprianidis A, Hattemer J, Engel U, Beli P, Bastians H, Acebrón SP. Proc Natl Acad Sci U S A. 2021 Aug 24; 118(34):e2108145118. doi:10.1073/pnas.2108145118.

PMID: 34417301

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Research Article

RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia

acute myeloid leukemia BMP drug resistance HSPC leukemia stem cell macrophages monocytes R-spondin self-renewal Wnt signaling
Sun R, He L, Lee H, Glinka A, Andresen C, Hübschmann D, Jeremias I, Müller-Decker K, Pabst C, Niehrs C. Cell Rep. 2021 Aug 17;36(7):109559. doi: 10.1016/j.celrep.2021.109559.
PMID: 34407399
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Research Article

The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra

Astacin Axis formation Hydra Proteinase Wnt signaling
Ziegler B, Yiallouros I, Trageser B, Kumar S, Mercker M, Kling S, Fath M, Warnken U, Schnölzer M, Holstein TW, Hartl M, Marciniak-Czochra A, Stetefeld J, Stöcker W, Özbek S. BMC Biol. 2021 Jun 9;19(1):120. 
PMID: 34107975
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Research Article

A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie–Wnt signaling axis in the liver

angiocrine factors liver endothelial cell (L-EC) phosphoproteomics proteomics Tie1 Tie2 transcriptomics vascular zonation Wnt signaling

Inverso D, Shi J, Lee KH, Jakab M, Ben-Moshe S, Kulkarni SR, Schneider M, Wang G, Komeili M, Vélez PA, Riedel M, Spegg C, Ruppert T, Schaeffer-Reiss C, Helm D, Singh I, Boutros M, Chintharlapalli S, Heikenwalder M, Itzkovitz S, Augustin HG. Dev Cell. 2021 Jun 7;56(11):1677-1693.e10.

PMID: 34038707

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Research Article

Quantitative Profiling of WNT-3A Binding to All Human Frizzled Paralogues in HEK293 Cells by NanoBiT/BRET Assessments

Frizzled NanoBRET Wnt signaling

Kozielewicz P, Shekhani R, Moser S, Bowin CF, Wesslowski J, Davidson G, Schulte G. ACS Pharmacol Transl Sci. 2021 May 11;4(3):1235-1245. doi: 10.1021/acsptsci.1c00084. eCollection 2021 Jun 11.

PMID: 34151213

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Research Article

USP42 protects ZNRF3/RNF43 from R‐spondin‐dependent clearance and inhibits Wnt signalling

colorectal cancer deubiquitination EMT LGR4/5/6 mouse intestinal organoids. Wnt signaling
Giebel N, de Jaime-Soguero A, García Del Arco A, Landry JJM, Tietje M, Villacorta L, Benes V, Fernández-Sáiz V, Acebrón SP. EMBO Rep. 2021 Mar 30:e51415. doi: 10.15252/embr.202051415. Online ahead of print.
PMID: 33786993
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Research Article

Wnt10b GSK3β dependent Wnt/STOP signaling prevents aneuploidy in human somatic cells

chromosome stability GSK3β Mitosis Wnt signaling Wnt/STOP Wnt10b
Lin YC, Haas A, Bufe A, Parbin S, Hennecke M, Voloshanenko O, Gross J, Boutros M, Acebron SP, Bastians H. Life Sci Alliance. 2020 Nov 30;4(1):e202000855. Print 2021 Jan.
PMID: 33257473
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Research Article

R-spondins are BMP receptor antagonists in Xenopus early embryonic development

BMP signaling embryonic development R-spondin Wnt signaling

Lee H, Seidl C, Sun R, Glinka A, Niehrs C. Nat Commun. 2020 Nov 4;11(1):5570. 

PMID: 33149137

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Research Article

The kinesin motor Klp98A mediates apical to basal Wg transport

endosomal trafficking kinesin transport transcytosis Wnt secretion Wnt signaling
Witte L, Linnemannstöns K, Schmidt K, Honemann-Capito M, Grawe F, Wodarz A, Gross JC. Development. 2020 Aug 14;147(15):dev186833. doi: 10.1242/dev.186833.
PMID: 32665246
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Research Article

Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium

endosomal sorting morphogen trafficking Wnt secretion Wnt signaling

Linnemannstöns K, Witte L, Karuna P, Kittel J, Danieli A, Müller D, Nitsch L, Honemann-Capito M, Grawe F, Wodarz A, Gross JC. Development. 2020 Aug 14;147(15):dev185421. PMID: 32611603

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