Publication Tag: Wnt signaling

Research Article

eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled

bioluminescence resonance energy transfer (BRET) Frizzled fusion protein G protein–coupled receptor (GPCR) ligand binding membrane protein NanoBiT NanoBRET trafficking Wnt signaling

Wesslowski J, Kozielewicz P, Wang X, Cui H, Schihada H, Kranz D, Karuna M P, Levkin P, Gross JC, Boutros M, Schulte G, Davidson G. J Biol Chem. 2020 May 7. pii: jbc.RA120.012892.

PMID:32381507

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Research Article

The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer

cell biology developmental biology human LRP6 PTPRK spemann organizer tyrosine phosphatase Wnt signaling xenopus ZNRF3

Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C. Elife. 2020 Jan 14;9. pii: e51248.

PMID: 31934854

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Research Article

Exocyst-mediated apical Wg secretion activates signaling in the Drosophila wing epithelium

Drosophila polarized epithelium Wg Wnt secretion Wnt signaling

Chaudhary V, Boutros M. PLoS Genet. 2019 Sep 17;15(9):e1008351.

PMID: 31527874

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Research Article

Robust Wnt signaling is maintained by a Wg protein gradient and Fz2 receptor activity in the developing Drosophila wing

Drosophila Frizzled Fz2 Morphogen gradient formation Protein secretion Wg Wing epithelium Wnt signaling

Chaudhary V, Hingole S, Frei J, Port F, Strutt D, Boutros M. Development. 2019 Aug 9;146(15).

PMID: 31399474

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Other

What makes flatworms go to pieces

flatworm regeneration Wnt signaling

Holstein TW. Nature. 2019 Aug;572(7771):593-594.

PMID: 31444489

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Research Article

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain

inflammation interferon modeling neural stem cells quiescence sFRP5 simulations single-cell transcriptomics stem cell aging subventricular zone Wnt signaling

Kalamakis G, Brüne D, Ravichandran S, Bolz J, Fan W, Ziebell F, Stiehl T, Catalá-Martinez F, Kupke J, Zhao S, Llorens-Bobadilla E, Bauer K, Limpert S, Berger B, Christen U, Schmezer P, Mallm JP, Berninger B, Anders S, Del Sol A, Marciniak-Czochra A, Martin-Villalba A. Cell. 2019 Mar 7;176(6):1407-1419.e14.

PMID: 30827680

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Research Article

Hydra Mesoglea Proteome Identifies Thrombospondin as a Conserved Component Active in Head Organizer Restriction

bilaterian cnidarian head organizer Hydra Wnt signaling

Lommel M, Strompen J, Hellewell AL, Balasubramanian GP, Christofidou ED, Thomson AR, Boyle AL, Woolfson DN, Puglisi K, Hartl M, Holstein TW, Adams JC, Özbek S. Sci Rep. 2018 Aug 6;8(1):11753.

PMID:30082916

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Research Article

Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates

cell biology cytonemes developmental biology patterning signaling filopodia trafficking Wnt signaling zebrafish

Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S. Elife. 2018 Jul 31;7.

PMID:30060804

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Research Article

Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification

Wnt signaling

Melnik S, Dvornikov D, Müller-Decker K, Depner S, Stannek P, Meister M, Warth A, Thomas M, Muley T, Risch A, Plass C, Klingmüller U, Niehrs C, Glinka A. Cell Discov. 2018 Jul 3;4:37.

PMID: 29977599

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Review

The Mingle-Mangle of Wnt Signaling and Extracellular Vesicles: Functional Implications for Heart Research

exosomes extracellular vesicles heart remodeling Wnt secretion Wnt signaling

Gross JC, Zelarayán LC. Front Cardiovasc Med. 2018 Feb 22;5:10.

PMID:29564334

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