Research Article
Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd
AML
BMP4 signaling
cell differentiation
dendrimer
development
peptides
R-spondin2
TSP1
Wnt signaling
xenopus
Lee H, Sun R, Niehrs C. J Biol Chem. 2022 Jan 12:101586. doi: 10.1016/j.jbc.2022.101586. Online ahead of print.
PMID: 35032551
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Research Article
The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer
cell biology
developmental biology
human
LRP6
PTPRK
spemann organizer
tyrosine phosphatase
Wnt signaling
xenopus
ZNRF3
Chang LS, Kim M, Glinka A, Reinhard C, Niehrs C. Elife. 2020 Jan 14;9. pii: e51248.
PMID: 31934854
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