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Mucociliary Wnt signaling promotes cilia biogenesis and beating

Cell signalling Ciliogenesis Wnt

Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C. Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2. PMID: 36878953

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Review

The role of Evi/Wntless in exporting Wnt proteins

cancer development Evi PORCN/Porcupine Wnt secretion Wnt signaling Wntless/Wls
Wolf L, Boutros M. Development. 2023 Feb 15;150(3):dev201352. doi: 10.1242/dev.201352. Epub 2023 Feb 10.
PMID: 36763105
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Research Article

Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis

cilia exencephaly GSK3 lipodystrophy LRP6 PP1 Wnt
Zhang K, Da Silva F, Seidl C, Wilsch-Bräuninger M, Herbst J, Huttner WB, Niehrs C. Dev Cell. 2023 Jan 23;58(2):139-154.e8. doi: 10.1016/j.devcel.2022.12.006. PMID: 36693320
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Research Article

Glycolytic flux-signaling controls mouse embryo mesoderm development

6-bisphosphate developmental biology flux-signaling metabolite fructose 1 metabolic signaling mouse presomitic mesoderm subcellular protein localization Wnt signaling

Miyazawa H, Snaebjornsson MT, Prior N, Kafkia E, Hammarén HM, Tsuchida-Straeten N, Patil KR, Beck M, Aulehla A. Elife. 2022 Dec 5;11:e83299. doi: 10.7554/eLife.83299. PMID: 36469462

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Research Article

Blockade of Wnt Secretion Attenuates Myocardial Ischemia-Reperfusion Injury by Modulating the Inflammatory Response

inflammation monocytes myocardial infarction Wnt signaling
Meyer IS, Li X, Meyer C, Voloshanenko O, Pohl S, Boutros M, Katus HA, Frey N, Leuschner F. Int J Mol Sci. 2022 Oct 14;23(20):12252. doi: 10.3390/ijms232012252.
PMID: 36293109
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Other

Analysis of Single-Cell Transcriptome Data in Drosophila

Computational methods Data analysis Droplet based Drosophila Seurat Single-cell RNA-seq Software packages
Yousefian S, Musillo MJ, Bageritz J. Methods Mol Biol. 2022;2540:93-111. doi: 10.1007/978-1-0716-2541-5_4. PMID: 35980574
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Research Article

Injury-induced MAPK activation triggers body axis formation in Hydra by default Wnt signaling

Axis formation injury response MAPK signaling regeneration Wnt/beta-catenin
Tursch A, Bartsch N, Mercker M, Schlüter J, Lommel M, Marciniak-Czochra A, Özbek S, Holstein TW. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2204122119. doi: 10.1073/pnas.2204122119. Epub 2022 Aug 22. PMID: 35994642
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Tissue-Specific CRISPR-Cas9 Screening in Drosophila

CRISPR/Cas9 Drosophila Genome editing Screening sgRNA libraries
Port F, Boutros M. Methods Mol Biol. 2022;2540:157-176. doi: 10.1007/978-1-0716-2541-5_7. PMID: 35980577
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Research Article

Superresolution microscopy localizes endogenous Dvl2 to Wnt signaling-responsive biomolecular condensates

biomolecular condensates CRISPR Dishevelled superresolution microscopy Wnt signaling

Schubert A, Voloshanenko O, Ragaller F, Gmach P, Kranz D, Scheeder C, Miersch T, Schulz M, Trümper L, Binder C, Lampe M, Engel U, Boutros M. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2122476119. doi: 10.1073/pnas.2122476119. Epub 2022 Jul 22. PMID: 35867833

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Review

Genetically encodable fluorescent protein markers in advanced optical imaging

fluorescence microscopy genetically encodable fluorescent markers GFP-type fluorescent protein super resolution microscopy tetrapyrrole-binding fluorescent protein
Nienhaus K, Nienhaus GU. Methods Appl Fluoresc. 2022 Jun 29. doi: 10.1088/2050-6120/ac7d3f. Online ahead of print.
PMID: 35767981
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