CRC 1324: Mechanisms and functions of Wnt signaling

Welcome to the website of the Collaborative Research Center (CRC) 1324 from Heidelberg University.

Who we are

The Collaborative Research Center 1324 is a DFG-funded interdisciplinary research consortium of about 60 scientists in 15 projects and three technology platforms. Our research focuses on the mechanisms and functions of Wnt signaling.

Within the framework of the interview series “Überlebensstragien” hosted by Heidelberg University and Rhein-Neckar-Fernsehen,

our CRC 1324 was represented by Michael Boutros and Josephine Bageritz:

https://www.uni-heidelberg.de/de/transfer/kommunikation/ueberlebensstrategien

Available on YouTube: https://www.youtube.com/watch?v=g52ttyWxoDk

Events

There are no upcoming events.

Publications

Research Article

Molecular dynamics of the matrisome across sea anemone life history

Cnidaria developmental biology evolutionary biology extracellular matrix matrisome nematostella vectensis sea anemone.

Bergheim BG, Cole AG, Rettel M, Stein F, Redl S, Hess MW, Ikmi A, Özbek S. Elife. 2025 Oct 23;14:RP105319. doi: 10.7554/eLife.105319.

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Research Article

Spatial multiomics of acute myocardial infarction reveals immune cell infiltration through the endocardium

Wünnemann F, Sicklinger F, Bestak K, Nimo J, Thiemann T, Amrute JM, Nordbeck M, Hartmann N, Ibarra-Arellano MA, Tanevski J, Chazotte M, Heine C, Frey N, Lavine KJ, Coscia F, Saez-Rodriguez J, Leuschner F, Schapiro D. Nat Cardiovasc Res. 2025 Oct;4(10):1345-1362. doi: 10.1038/s44161-025-00717-y. Epub 2025 Oct 3.

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Join the CRC 1324

Wnt Young Investigator program

We are searching for exceptional early career scientists with a research interest in Wnt signaling to apply for independent junior group funding.

Herbert Steinbeisser Fellowships

In memory of Professor Dr. Herbert Steinbeisser, the SFB1324 offers fellowships to support medical students during experimental research projects that comprise part of their M.D. thesis. Further information can be found here: SFB1324 Herbert Steinbeisser Fellowships

Applications can be submitted twice annually, by June 15th and December 15th.