Research Article
CRC 1324: Mechanisms and functions of Wnt signaling
Welcome to the website of the Collaborative Research Center (CRC) 1324 from Heidelberg University.
Who we are
The Collaborative Research Center 1324 is a DFG-funded interdisciplinary research consortium of about 60 scientists in 14 projects and three technology platforms. Our research focuses on the mechanisms and functions of Wnt signaling.
Within the framework of the interview series “Überlebensstragien” hosted by Heidelberg University and Rhein-Neckar-Fernsehen,
our CRC 1324 was represented by Michael Boutros and Josephine Bageritz:
https://www.uni-heidelberg.de/de/transfer/kommunikation/ueberlebensstrategien
Available on YouTube: https://www.youtube.com/watch?v=g52ttyWxoDk
Publications
Research Article
Mutual inhibition model of pattern formation: The role of Wnt-Dickkopf interactions in driving Hydra body axis formation
PLoS Comput Biol. 2026 Jul 13;22(7):e1014416. doi: 10.1371/journal.pcbi.1014416. eCollection 2026 Jul. PMID: 42441669
Join the CRC 1324
Open PhD position
- Prof. Michael Boutros (Project Z03):
– Development and application of advanced CRISPR genome engineering methods
– Technology development
– Transferability of methods across experimental systems
– Further information: HBIGS
Herbert Steinbeisser M.D. Fellowships
In memory of Professor Dr. Herbert Steinbeisser, the SFB 1324 offers fellowships to support medical students during experimental research projects that comprise part of their M.D. thesis. Further information can be found here:
Herbert Steinbeisser Fellowship
Applications can be submitted until June 1st 2026.
News
ERC Proof of concept grant
Prof. Hellmut Augustin received Proof of concept grant from the European Research Council (ERC) for SpheroMouse. The project aims to validate a versatile platform of novel standardized and biobankable preclinical mouse tumor models. Press Release ERC Press Release: https://www.dkfz.de/en/news/press-releases/detail/double-erc-success-for-dkfz-researchers-1
Learn more
SFB1324 – 3rd funding period
Our SFB1324 has been granted funding by the DFG:
https://www.uni-heidelberg.de/en/newsroom/universitat-heidelberg-succeeds-with-three-funding-applications-for-collaborative-research-centres
“Überlebensstragien”
Hosted by Heidelberg University and Rhein-Neckar-Fernsehen:
https://www.uni-heidelberg.de/de/transfer/kommunikation/
Wnt Meeting 2024
Thanks everyone for the positive feedback we received for our Wnt Meeting in Heidelberg (September 25-27, 2024). Christoph Bastert Photography, 2024.
Learn more