CRC 1324: Mechanisms and functions of Wnt signaling

Welcome to the website of the Collaborative Research Center (CRC) 1324 from Heidelberg University.

Who we are

The Collaborative Research Center 1324 is a DFG-funded interdisciplinary research consortium of about 60 scientists in 15 projects and three technology platforms. Our research focuses on the mechanisms and functions of Wnt signaling.



Wnt Seminar

Marina Mapelli (IRCCS, Milan):
“Molecular crosstalk between fate determination and Wnt-dependent orientation in epithelial cell divisions”

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Research Article

A predatory gastrula leads to symbiosis-independent settlement in Aiptasia.

Maegele I, Rupp S, Özbek S, Guse A, Hambleton EA, Holstein TW. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2311872120. doi: 10.1073/pnas.2311872120. Epub 2023 Sep 25. PMID: 37748072
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Research Article

A temperature-tolerant CRISPR base editor mediates highly efficient and precise gene editing in Drosophila

Doll RM, Boutros M, Port F. Sci Adv. 2023 Sep;9(35):eadj1568. doi: 10.1126/sciadv.adj1568. Epub 2023 Aug 30. PMID: 37647411

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Join the CRC 1324

Wnt Young Investigator program

We are searching for exceptional early career scientists with a research interest in Wnt signaling to apply for independent junior group funding.

Further information can be found here: Wnt_YIP

Application deadline September 01, 2022

Herbert Steinbeisser Fellowships

In memory of Professor Dr. Herbert Steinbeisser, the SFB1324 offers fellowships to support medical students during experimental research projects that comprise part of their M.D. thesis. Further information can be found here: SFB1324 Herbert Steinbeisser Fellowships

Applications can be submitted twice annually, by June 15th and December 15th.


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