CRC 1324: Mechanisms and functions of Wnt signaling

Welcome to the website of the Collaborative Research Center (CRC) 1324 from Heidelberg University.

Who we are

The Collaborative Research Center 1324 is a DFG-funded interdisciplinary research consortium of about 60 scientists in 15 projects and three technology platforms. Our research focuses on the mechanisms and functions of Wnt signaling.



Research Article

Mucociliary Wnt signaling promotes cilia biogenesis and beating

Cell signalling Ciliogenesis Wnt

Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C. Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2. PMID: 36878953

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The role of Evi/Wntless in exporting Wnt proteins

cancer development Evi PORCN/Porcupine Wnt secretion Wnt signaling Wntless/Wls
Wolf L, Boutros M. Development. 2023 Feb 15;150(3):dev201352. doi: 10.1242/dev.201352. Epub 2023 Feb 10.
PMID: 36763105
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Join the CRC 1324

Wnt Young Investigator program

We are searching for exceptional early career scientists with a research interest in Wnt signaling to apply for independent junior group funding.

Further information can be found here: Wnt_YIP

Application deadline September 01, 2022

Herbert Steinbeisser Fellowships

In memory of Professor Dr. Herbert Steinbeisser, the SFB1324 offers fellowships to support medical students during experimental research projects that comprise part of their M.D. thesis. Further information can be found here: SFB1324 Herbert Steinbeisser Fellowships

Applications can be submitted twice annually, by June 15th and December 15th.


ERC Synergy Grant

Anna Marciniak-Czochra and Ana Martin-Villalba together with Simon Anders (Heidelberg University) and Laure Bally-Cuif (Institut Pasteur in Paris) received an ERC Synergy Grant.

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