CRC 1324: Mechanisms and functions of Wnt signaling

Welcome to the website of the Collaborative Research Center (CRC) 1324 from Heidelberg University.

Who we are

The Collaborative Research Center 1324 is a DFG-funded interdisciplinary research consortium of about 60 scientists in 15 projects and three technology platforms. Our research focuses on the mechanisms and functions of Wnt signaling.



SFB 1324 Retreat

Young Scientists and PI Meeting

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The role of cnidarian developmental biology in unraveling axis formation and Wnt signaling.

Axis formation Gradients Hydra Nematostella Nodal signaling Tgf-beta signaling Wnt signaling

Holstein TW. Dev Biol. 2022 Apr 22;487:74-98. doi: 10.1016/j.ydbio.2022.04.005. Online ahead of print.

PMID: 35461834

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Cross-Talk between p53 and Wnt Signaling in Cancer

APC beta-catenin cancer drug resistance metastasis p53 Wnt

Xiao Q, Werner J, Venkatachalam N, Boonekamp KE, Ebert MP, Zhan T. Biomolecules. 2022 Mar 15;12(3):453. doi: 10.3390/biom12030453. PMID: 35327645

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Join the CRC 1324

Wnt Young Investigator program

We are searching for exceptional early career scientists with a research interest in Wnt signaling to apply for independent junior group funding.

Further information can be found here: WNT_YIP

Application deadline March 31, 2022

Herbert Steinbeisser Fellowships

In memory of Professor Dr. Herbert Steinbeisser, the SFB1324 offers fellowships to support medical students during experimental research projects that comprise part of their M.D. thesis. Further information can be found here: SFB1324 Herbert Steinbeisser Fellowships

Applications can be submitted twice annually, by June 15th and December 15th.


Follow us on

Tweets about latest publications, announcements and events on #Wnt signaling.

We are looking for highly motivated and enthusiastic students (MSc or MD) to join our group to work on #Wnt signaling and extracellular vesicles in cancer. Great opportunity to join the @DKFZ and @sfb1324!

Please RT.

@_A_Schubert @NCT_HD
#EV #Heidelberg