Dr. Ulrike Engel

Project Leader Z02

Nikon Imaging Center (BioQuant)
and Centre for Organismal Studies (COS)
Heidelberg University

ulrike.engel@bioquant.uni-heidelberg.de

https://www.uni-heidelberg.de/nic/index.html

Professional Career

since 2005

Head of the Nikon Imaging Center

Heidelberg University, Heidelberg

since 2005

Project group leader

Department of Molecular Evolution & Genomics, COS, Heidelberg University

2002-2005

Postdoctoral fellow

Department of Cell Biology, Harvard Medical School, Boston, USA

2001

Dr. rer. nat.

Technical University Darmstadt, Prof. Dr. Th. Holstein

1996

Diploma in Biology

University of Basel, Switzerland; Advisor: Prof. Dr. Th. Boller

Achievements & Awards

2011-2017

Steering committee

emerging collaborative topic ‘Spatio-temporal coordination of signaling processes’, CellNetworks, Heidelberg University

2008-2019

Member

Excellence Cluster ‘CellNetworks’, Heidelberg University

2004-2005

Post-doctoral Scholarship

Swiss National Science Foundation (Stipendium für fortgeschrittene Forschende)

2003

Post-doctoral Scholarship

Swiss National Science Foundation (Stipendium für angehende Forschende)

2002

Cold Spring Harbor Laboratory Course

‘Imaging structure and function in the nervous system’

Publications

Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress

de Jaime-Soguero A, Hattemer J, Bufe A, Haas A, van den Berg J, van Batenburg V, Das B, di Marco B, Androulaki S, Böhly N, Landry JJM, Schoell B, Rosa VS, Villacorta L, Baskan Y, Trapp M, Benes V, Chabes A, Shahbazi M, Jauch A, Engel U, Patrizi A, Sotillo R, van Oudenaarden A, Bageritz J, Alfonso J, Bastians H, Acebrón SP. Nat Commun. 2024 Aug 28;15(1):7404. doi: 10.1038/s41467-024-51821-9. PMID: 39191776

Learn more
Wnt/β-catenin signaling induces axial elasticity patterns of Hydra extracellular matrix

Veschgini M, Suzuki R, Kling S, Petersen HO, Bergheim BG, Abuillan W, Linke P, Kaufmann S, Burghammer M, Engel U, Stein F, Özbek S, Holstein TW, Tanaka M. iScience. 2023 Mar 16;26(4):106416. doi: 10.1016/j.isci.2023.106416. eCollection 2023 Apr 21. PMID: 37009232

Learn more
Superresolution microscopy localizes endogenous Dvl2 to Wnt signaling-responsive biomolecular condensates

Schubert A, Voloshanenko O, Ragaller F, Gmach P, Kranz D, Scheeder C, Miersch T, Schulz M, Trümper L, Binder C, Lampe M, Engel U, Boutros M. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2122476119. doi: 10.1073/pnas.2122476119. Epub 2022 Jul 22. PMID: 35867833

Learn more
Wnt signaling recruits KIF2A to the spindle to ensure chromosome congression and alignment during mitosis

Bufe A, García Del Arco A, Hennecke M, de Jaime-Soguero A, Ostermaier M, Lin YC, Ciprianidis A, Hattemer J, Engel U, Beli P, Bastians H, Acebrón SP. Proc Natl Acad Sci U S A. 2021 Aug 24; 118(34):e2108145118. doi:10.1073/pnas.2108145118. PMID: 34417301

Learn more
Characterization of spindle pole body duplication reveals a regulatory role for nuclear pore complexes

Rüthnick D, Neuner A, Dietrich F, Kirrmaier D, Engel U, Knop M, Schiebel E. J Cell Biol. 2017 Aug 7;216(8):2425-2442. doi: 10.1083/jcb.201612129. Epub 2017 Jun 28. PMID: 28659328

Learn more
Four-Channel Super-Resolution Imaging by 3-D Structured Illumination

Engel U. Methods Mol Biol. 2017;1663:79-94. doi: 10.1007/978-1-4939-7265-4_7.
PMID: 28924660

Learn more
Early Commissural Diencephalic Neurons Control Habenular Axon Extension and Targeting

Beretta CA, Dross N, Guglielmi L, Bankhead P, Soulika M, Gutierrez-Triana JA, Paolini A, Poggi L, Falk J, Ryu S, Kapsimali M, Engel U, Carl M. Curr Biol. 2017 Jan 23;27(2):270-278. doi: 10.1016/j.cub.2016.11.038. Epub 2017 Jan 5. PMID: 28065605

Learn more