Prof. Dr. Julia Gross

Project Leader A03

Professor of Biochemistry
HMU - Health and Medical University Potsdam
Villa Carlshagen
Olympischer Weg 1
14471 Potsdam

julia.gross@health-and-medical-university.de

https://www.extracellular-signaling-lab.de/
Prof. Dr. Julia Gross

Professional Career

Since 10/2020

Professor of Biochemistry

HMU Potsdam

2019 – 2021

Stand-in professor

Biochemistry, UMG Göttingen

2015 – 2019

Junior Group Leader

Haematology and Oncology/UMG and Developmental Biochemistry / Göttingen Center for Molecular Biosciences (GZMB), Göttingen

2010-2015

Postdoctoral scientist

Deutsches Krebsforschungszentrum and Heidelberg University, Heidelberg

2009

Dr. phil. nat. in Biology

Goethe University, Frankfurt

2005

Diploma in Biology

Goethe University, Frankfurt

Achievements & Awards

2017

Member of the steering committee

DFB Collaborative Research Center CRC1324 “Mechanisms and functions of Wnt Signaling”

2017

Heidenreich von Siebold Habilitationsprogramm

UMG, Göttingen

2010 – 2012

Postdoctoral Fellowship

CellNetworks Excellence Cluster, Heidelberg

2006 – 2008

Promotionsstipendium

Evangelisches Studienwerk Villigst

2005

Promotionsstipendium

Center of Membrane Proteomics, Frankfurt a. M.

2001 – 2005

Begabtenförderung

Evangelisches Studienwerk Villigst

Publications

Wnt10b GSK3β dependent Wnt/STOP signaling prevents aneuploidy in human somatic cells

Lin YC, Haas A, Bufe A, Parbin S, Hennecke M, Voloshanenko O, Gross J, Boutros M, Acebron SP, Bastians H. Life Sci Alliance. 2020 Nov 30;4(1):e202000855. Print 2021 Jan.
PMID: 33257473

Learn more
Phosphorylation of Ykt6 SNARE Domain Regulates Its Membrane Recruitment and Activity

Karuna M P, Witte L, Linnemannstoens K, Choezom D, Danieli-Mackay A, Honemann-Capito M, Gross JC. Biomolecules. 2020 Nov 16;10(11):E1560.

PMID: 33207719

Learn more
The kinesin motor Klp98A mediates apical to basal Wg transport

Witte L, Linnemannstöns K, Schmidt K, Honemann-Capito M, Grawe F, Wodarz A, Gross JC. Development. 2020 Aug 14;147(15):dev186833. doi: 10.1242/dev.186833.
PMID: 32665246

Learn more
Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium

Linnemannstöns K, Witte L, Karuna P, Kittel J, Danieli A, Müller D, Nitsch L, Honemann-Capito M, Grawe F, Wodarz A, Gross JC. Development. 2020 Aug 14;147(15):dev185421. PMID: 32611603

Learn more
eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled

Wesslowski J, Kozielewicz P, Wang X, Cui H, Schihada H, Kranz D, Karuna M P, Levkin P, Gross JC, Boutros M, Schulte G, Davidson G. J Biol Chem. 2020 May 7. pii: jbc.RA120.012892. PMID:32381507

Learn more
The Mingle-Mangle of Wnt Signaling and Extracellular Vesicles: Functional Implications for Heart Research

Gross JC, Zelarayán LC. Front Cardiovasc Med. 2018 Feb 22;5:10. PMID:29564334

Learn more
Neutral sphingomyelinases control extracellular vesicles budding from the plasma membrane

Menck K, Sönmezer C, Worst TS, Schulz M, Dihazi GH, Streit F, Erdmann G, Kling S, Boutros M, Binder C, Gross JC. J Extracell Vesicles. 2017 Sep 26;6(1):1378056. doi: 10.1080/20013078.2017.1378056. eCollection 2017. PMID: 29184623

Learn more
Biochemical Methods to Analyze Wnt Protein Secretion

Glaeser K, Boutros M, Gross JC. Methods Mol Biol. 2016;1481:17-28. doi: 10.1007/978-1-4939-6393-5_3. PMID: 27590148

Learn more
Molecular dissection of Wnt3a-Frizzled8 interaction reveals essential and modulatory determinants of Wnt signaling activity

Kumar S, Žigman M, Patel TR, Trageser B, Gross JC, Rahm K, Boutros M, Gradl D, Steinbeisser H, Holstein T, Stetefeld J, Özbek S. BMC Biol. 2014 May 30;12:44. doi: 10.1186/1741-7007-12-44. PMID: 24885675

Learn more
Active Wnt proteins are secreted on exosomes

Gross JC, Chaudhary V, Bartscherer K, Boutros M. Nat Cell Biol. 2012 Oct;14(10):1036-45. doi: 10.1038/ncb2574. Epub 2012 Sep 16. PMID: 22983114

Learn more