Prof. Dr. Anna Marciniak-Czochra

Project Leader B05

Heidelberg University
Institute of Applied Mathematics
Im Neuenheimer Feld 205
69120 Heidelberg

Prof. Dr. Anna Marciniak-Czochra

Professional Career

since 2016

Director of the Institute of Applied Mathematics

Heidelberg University

since 2011

Full Professor (W3) of Applied Analysis

Faculty of Mathematics and Computer Sciences and an associated member of the Interdisciplinary Center of Scientific Computing (IWR), Heidelberg University


Visiting Professor

Department of Mathematics, University of Lyon, France


Dr. habil.

University of Wroclaw, Wroclaw, Poland


Independent Research Group Leader

ERC Starting Grant and Emmy-Noether- Group, IWR and BIOQUANT, Heidelberg University


Visiting Faculty Member

Mathematical Bioscience Institute, Columbus Ohio, USA


Project leader

Heidelberg Academy of Sciences and Humanities (WIN Kolleg)


Postdoctoral project leader

Center for Modeling and Simulation in Biosciences (BIOMS), IWR, Heidelberg University


Dr. rer. nat.

Heidelberg University; Advisor: Prof. Dr. Dr. h.c. mult. Willi Jäger


Diploma (mgr) in mathematics

University of Warsaw, Poland; Advisor: Prof. Dr. M.Lachowicz

Achievements & Awards


ERC Synergy Grant

“PerPetuating Stemness: From single-cell analysis to mechanistic spatio-temporal models of neural stem cell dynamics” (PEPS)

since 2020


Commission for Research and Strategy, Heidelberg University

since 2020

Member of the Board

Flagship Initiative Engineering Molecular Systems (Fl EMS) of the Excellence Strategy of Heidelberg University

since 2019

Elected representativeat the Senat

Heidelberg University

since 2019

Principal Investigator

“Structures” Cluster of Excellence (DFG), Heidelberg University



Marsilius Kolleg, Heidelberg University

since 2019

International Scientific Advisory Board

Center for Advanced Systems Understanding (CASUS), Görlitz

since 2018

ESMTB representative

European Mathematical Society (EMS)


Simons Professor

Mathematical Institute, Polish Academy of Sciences, Warsaw


Organising Committee

Year of Mathematical Biology 2018 (EMS/ESMTB)

since 2014

Member of the Research Council

Interdisciplinary Field of Focus “Structure and pattern formation in the material world”, Excellence Initiative, Heidelberg University

since 2014

Member of the Executive Board

Heidelberg Graduate School of Mathematical and Computational Methods for the Sciences (HGS), Heidelberg University

since 2014

Board Member

ESMTB (European Society of Mathematical and Theoretical Biology)


Board Member

Mathematics Center Heidelberg (MATCH), Heidelberg University



Kollegiates of Heidelberg Academy of Sciences and Humanities


Deputy Director

Institute of Applied Mathematics, Heidelberg University



Heidelberg Academy of Sciences and Humanities

since 2010

Principal Investigator

DFG Collaborative Research Center 873 (SFB 873)


AcademiaNet Portal

Outstanding Female Scientists and Scholars of Robert Bosch Foundation (nominated by DFG)



German Research Council (DFG)


ERC Starting Grant

European Research Council



Heidelberg Academy of Science and Humanities


Injury-induced MAPK activation triggers body axis formation in Hydra by default Wnt signaling

Tursch A, Bartsch N, Mercker M, Schlüter J, Lommel M, Marciniak-Czochra A, Özbek S, Holstein TW. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2204122119. doi: 10.1073/pnas.2204122119. Epub 2022 Aug 22. PMID: 35994642

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The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra

Ziegler B, Yiallouros I, Trageser B, Kumar S, Mercker M, Kling S, Fath M, Warnken U, Schnölzer M, Holstein TW, Hartl M, Marciniak-Czochra A, Stetefeld J, Stöcker W, Özbek S. BMC Biol. 2021 Jun 9;19(1):120. 
PMID: 34107975

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Long-time shadow limit for a reaction–diffusion-ODE system

Kowall, C., A. Marciniak-Czochra, and A. Mikelic. February 2021. Applied Mathematics Letters. 106790.

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Hysteresis-driven pattern formation in reaction-diffusion-ODE systems

Alexandra Köthe, Anna Marciniak-Czochra  and  Izumi Takagi. American Institute of Mathematical Science. June  2020, 40(6): 3595-3627. doi: 10.3934/dcds.2020170

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Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain

Kalamakis G, Brüne D, Ravichandran S, Bolz J, Fan W, Ziebell F, Stiehl T, Catalá-Martinez F, Kupke J, Zhao S, Llorens-Bobadilla E, Bauer K, Limpert S, Berger B, Christen U, Schmezer P, Mallm JP, Berninger B, Anders S, Del Sol A, Marciniak-Czochra A, Martin-Villalba A. Cell. 2019 Mar 7;176(6):1407-1419.e14. PMID: 30827680

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Post-Turing tissue pattern formation: Advent of mechanochemistry

Brinkmann F, Mercker M, Richter T, Marciniak-Czochra A. PLoS Comput Biol. 2018 Jul 3;14(7):e1006259. PMID:29969460

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Dynamical spike solutions in a nonlocal model of pattern formation

Marciniak-Czochra, S. Härting, G. Karch and K. Suzuki (2018, Mar 27), Nonlinearity 31: 1757.

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Revealing age related changes of adult hippocampal neurogenesis using mathematical models

Ziebell F, Dehler S, Martin-Villalba A, Marciniak-Czochra A. Development. 2018 Jan 8;145(1):dev153544. doi: 10.1242/dev.153544. PMID: 29229768

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Stable patterns with jump discontinuity in systems with Turing instability and hysteresis

Härting, S., A. Marciniak-Czochra, and I. Takagi. February 2017. Disc. Cont. Dyn. Systems A. 37: 757-800.

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Mechanochemical symmetry breaking in Hydra aggregates

Mercker M, Köthe A, Marciniak-Czochra A. Biophys J. 2015 May 5;108(9):2396-407. doi: 10.1016/j.bpj.2015.03.033. PMID: 25954896

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A mechanochemical model for embryonic pattern formation: Coupling tissue mechanics and morphogen expression

Mercker M, Hartmann D, Marciniak-Czochra A. PLoS One. 2013 Dec 20;8(12):e82617. doi: 10.1371/journal.pone.0082617. eCollection 2013. PMID: 24376555

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