Apl. Prof. Dr. Suat Özbek
Project Leader B07
Heidelberg University
Centre for Organismal Studies (COS)
Department Molecular Evolution and Genomics
Im Neuenheimer Feld 230
D-69120 Heidelberg
suat.oezbek@cos.uni-heidelberg.de

Professional Career
2017
Adjunct Professor
Heidelberg University
2011
Permanent position
as Senior Lecturer and group leader (COS), Dept. Molecular Evolution and Genomics, Heidelberg University
2005
Group leader
Zoological Institute Heidelberg University
2004
Habilitation in Biochemistry/Biophysics
University of Basel, Switzerland
2000
Postdoc
Biozentrum Basel, Switzerland, with Prof. Dr. Jürgen Engel
2000
PhD
University of Mainz, Advisor: Prof. Dr. Stefan Rose-John
Achievements & Awards
Publications
A predatory gastrula leads to symbiosis-independent settlement in Aiptasia.
Wnt/β-catenin signaling induces axial elasticity patterns of Hydra extracellular matrix
Injury-induced MAPK activation triggers body axis formation in Hydra by default Wnt signaling
The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra
Wnt/β-Catenin Signaling Controls Spatio-Temporal Elasticity Patterns in Extracellular Matrix during Hydra Morphogenesis
Veschgini, M., H.O. Petersen, F. Rossetti, W. Abuillan, S. Kaufmann, R. Suzuki, M. Burghammer, S. Özbek, T.W. Holstein, and M. Tanaka. 2020. bioRxiv, preprint.
Learn moreHydra Mesoglea Proteome Identifies Thrombospondin as a Conserved Component Active in Head Organizer Restriction
Lommel M, Strompen J, Hellewell AL, Balasubramanian GP, Christofidou ED, Thomson AR, Boyle AL, Woolfson DN, Puglisi K, Hartl M, Holstein TW, Adams JC, Özbek S. Sci Rep. 2018 Aug 6;8(1):11753. PMID:30082916
Learn moreWnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates
Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S. Elife. 2018 Jul 31;7. PMID:30060804
Learn moreSecreted Frizzled-related Protein 2 (sFRP2) Redirects Non-canonical Wnt Signaling from Fz7 to Ror2 during Vertebrate Gastrulation
J Biol Chem. 2016 Jun 24;291(26):13730-42. doi: 10.1074/jbc.M116.733766. Epub 2016 Apr 29. PMID: 27129770
Learn moreA Comprehensive Transcriptomic and Proteomic Analysis of Hydra Head Regeneration.
Petersen, H.O., S.K. Hoger, M. Looso, T. Lengfeld, A. Kuhn, U. Warnken, C. Nishimiya-Fujisawa, M. Schnolzer, M. Kruger, S. Ozbek, O. Simakov, and T.W. Holstein. Mol Biol Evol. 2015 Aug;32(8):1928-47. doi: 10.1093/molbev/msv079. Epub 2015 Apr 3. PMID: 25841488
Learn moreNodal signalling determines biradial asymmetry in Hydra
Molecular dissection of Wnt3a-Frizzled8 interaction reveals essential and modulatory determinants of Wnt signaling activity
BMC Biol. 2014 May 30;12:44. doi: 10.1186/1741-7007-12-44. PMID: 24885675
Learn moreAutoregulatory and repressive inputs localize Hydra Wnt3 to the head organizer
Proc Natl Acad Sci U S A. 2011 May 31;108(22):9137-42. doi: 10.1073/pnas.1018109108. Epub 2011 May 16. PMID: 21576458
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