Dr. med. Tianzuo Zhan
Project Leader B08
Heidelberg University
Medical Faculty Mannheim
Mannheim University Hospital
Department of Medicine II
Theodor-Kutzer-Ufer 1-3
D-68167 Mannheim
tianzuo.zhan@umm.de

Professional Career
since 2019
Fellow
DFG-Clinician Scientist Program “Interfaces and Interventions in Complex Chronic Conditions”, Heidelberg University, Medical Faculty Mannheim
since 2019
Junior Research Group Leader “Translational GI Oncology”
Department of Medicine II, Mannheim University Hospital, Mannheim
2013 - 2018
Postdoctoral research fellow,
Division Signaling and Functional Genomics, German Cancer Research Center, Heidelberg
since 2012
Training in Internal Medicine
Department of Medicine II, Mannheim University Hospital, Mannheim
2011
MD degree
Heidelberg University
Achievements & Awards
2020
Travel grant
German Cancer Aid, and best abstract selection, German Cancer Congress
2019
Cancer Research award
Oncology Working Group Mannheim
2018
Adolf Kußmaul award
Southwest German Society of Gastroenterology
2016
Otto Porges abstract award
German Society for Digestive and Metabolic Diseases
2013
Fellowship grant
DKFZ International Postdoc Program
2011
Travel grant
best doctoral thesis, German Society for Digestive and Metabolic Diseases
2004-2011
Scholarship
German National Academic Foundation
Publications
The Roles of Secreted Wnt Ligands in Cancer
Int J Mol Sci. 2023 Mar 10;24(6):5349. doi: 10.3390/ijms24065349. PMID: 36982422
Learn moreCross-Talk between p53 and Wnt Signaling in Cancer
Biomolecules. 2022 Mar 15;12(3):453. doi: 10.3390/biom12030453. PMID: 35327645
Learn moreMulti-omics integration identifies a selective vulnerability of colorectal cancer subtypes to YM155
MEK inhibitors activate Wnt signalling and induce stem cell plasticity in colorectal cancer
Nat Commun. 2019 May 16;10(1):2197. doi: 10.1038/s41467-019-09898-0. PMID: 31097693
Learn moreCRISPR/Cas9 for cancer research and therapy
Semin Cancer Biol. 2019 Apr;55:106-119. doi: 10.1016/j.semcancer.2018.04.001. Epub 2018 Apr 16. PMID: 29673923
Learn moreWnt signaling in cancer
Oncogene. 2017 Mar;36(11):1461-1473. doi: 10.1038/onc.2016.304. Epub 2016 Sep 12. PMID: 27617575
Learn moreCRISPRlibrary designer (CLD): software for multispecies design of single guide RNA libraries.
Genome Biol. 2016 Mar 24;17:55. doi: 10.1186/s13059-016-0915-2. PMID: 27013184
Learn more