Publications

Research Article

Robust Wnt signaling is maintained by a Wg protein gradient and Fz2 receptor activity in the developing Drosophila wing

Drosophila Frizzled Fz2 Morphogen gradient formation Protein secretion Wg Wing epithelium Wnt signaling

Chaudhary V, Hingole S, Frei J, Port F, Strutt D, Boutros M. Development. 2019 Aug 9;146(15).

PMID: 31399474

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Other

What makes flatworms go to pieces

flatworm regeneration Wnt signaling

Holstein TW. Nature. 2019 Aug;572(7771):593-594.

PMID: 31444489

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Research Article

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain

inflammation interferon modeling neural stem cells quiescence sFRP5 simulations single-cell transcriptomics stem cell aging subventricular zone Wnt signaling

Kalamakis G, Brüne D, Ravichandran S, Bolz J, Fan W, Ziebell F, Stiehl T, Catalá-Martinez F, Kupke J, Zhao S, Llorens-Bobadilla E, Bauer K, Limpert S, Berger B, Christen U, Schmezer P, Mallm JP, Berninger B, Anders S, Del Sol A, Marciniak-Czochra A, Martin-Villalba A. Cell. 2019 Mar 7;176(6):1407-1419.e14.

PMID: 30827680

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Research Article

Enhanced in vivo-imaging in medaka by optimized anaesthesia, fluorescent protein selection and removal of pigmentation

CRISPR/Cas9 in vivo-imaging zebrafish

Lischik CQ, Adelmann L, Wittbrodt J. PLoS One. 2019 Mar 7;14(3):e0212956.

PMID: 30845151

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Research Article

Hydra Mesoglea Proteome Identifies Thrombospondin as a Conserved Component Active in Head Organizer Restriction

bilaterian cnidarian head organizer Hydra Wnt signaling

Lommel M, Strompen J, Hellewell AL, Balasubramanian GP, Christofidou ED, Thomson AR, Boyle AL, Woolfson DN, Puglisi K, Hartl M, Holstein TW, Adams JC, Özbek S. Sci Rep. 2018 Aug 6;8(1):11753.

PMID:30082916

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Research Article

Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates

cell biology cytonemes developmental biology patterning signaling filopodia trafficking Wnt signaling zebrafish

Mattes B, Dang Y, Greicius G, Kaufmann LT, Prunsche B, Rosenbauer J, Stegmaier J, Mikut R, Özbek S, Nienhaus GU, Schug A, Virshup DM, Scholpp S. Elife. 2018 Jul 31;7.

PMID:30060804

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Research Article

Post-Turing tissue pattern formation: Advent of mechanochemistry

modeling patterning

Brinkmann F, Mercker M, Richter T, Marciniak-Czochra A. PLoS Comput Biol. 2018 Jul 3;14(7):e1006259.

PMID:29969460

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Research Article

Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification

Wnt signaling

Melnik S, Dvornikov D, Müller-Decker K, Depner S, Stannek P, Meister M, Warth A, Thomas M, Muley T, Risch A, Plass C, Klingmüller U, Niehrs C, Glinka A. Cell Discov. 2018 Jul 3;4:37.

PMID: 29977599

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Other

Making head or tail of cnidarian hox gene function

bilaterian evolution patterning

Rentzsch F, Holstein TW. Nat Commun. 2018 Jun 5;9(1):2187.

PMID:29872045

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Research Article

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium

computational biology developmental biology DNA methylation endothelial epigenome endothelial quiescence endothelial trsanscriptome human mouse stem cells systems biology TGFß

Schlereth K, Weichenhan D, Bauer T, Heumann T, Giannakouri E, Lipka D, Jaeger S, Schlesner M, Aloy P, Eils R, Plass C, Augustin HG. Elife. 2018 May 11;7.

PMID:29749927

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Other

A Cell-Based Assay for Mitotic Spindle Orientation

Dimethylenastron Immunostaining Mitosis Monopolar spindle structure Spindle orientation.

Glaubke E, Bastians H. Methods Mol Biol. 2018;1787:67-75. doi: 10.1007/978-1-4939-7847-2_5.

PMID:29736710

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Research Article

Dynamical spike solutions in a nonlocal model of pattern formation

Marciniak-Czochra, S. Härting, G. Karch and K. Suzuki (2018, Mar 27), Nonlinearity 31: 1757.

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